Research Articles

As part of our goal to raise awareness of pancreatic cancer, the Rolfe Foundation makes a point to stay on top of relevant news in the media, and to share stories of progress with our supporters. Here, you can find reports about recent advances in pancreatic cancer research.

April 2019

04/31/2019 - Journal of Clinical Pathways. Episode 10: Advances in Pancreatic Cancer With Anirban Maitra. Listen to this healthcare podcast as Chadi Nabhan, MD, MBA, FACP, and Anirban Maitra, MD, director of pancreatic cancer research, The University of Texas MD Anderson Cancer Center, break down important touch points of screening in Pancreatic Cancer. They also discuss future research topics in adjuvant and metastatic setting and funding opportunities for junior investigators.

March 2019

03/31/2019 - ScienceDaily. Excess Body Weight Before 50 is Associated With Higher Risk Of Dying From Pancreatic Cancer. Excess weight before age 50 may be more strongly associated with pancreatic cancer mortality risk than excess weight at older ages, according to results of a study presented at the AACR Annual Meeting 2019, March 29-April 3. 

February 2019

02/19/2019 - OncLive. The Changing Landscape of Pancreatic Cancer Treatment. Watch as discuss the changing landscape of Pancreatic Cancer Treatments. Insights From: Tony Saab, MD, Mayo Clinic; Davendra Sohal, MD, MPH, Cleveland Clinic

02/10/2019 - ABC6. American Cancer Society: Cancers Seen in Older Adults on the Rise in Millennials. The incidence of six cancers, known to be related to obesity, has gone up significantly. They include Multiple Myeloma, Colorectal, Gallbladder, Kidney, Uterine and Pancreatic cancers. The biggest increase in pancreatic cancer was among 25 to 29-year-olds.

02/09/2019 - TribLive. AHN, Johns Hopkins Researchers To Study Obesity, Pancreatic Cancer. Researchers at Allegheny Health Network Cancer Institute and Johns Hopkins Kimmel Cancer Center are teaming up to study the link between obesity and pancreatic cancer.

02/01/2019 - News Medical Life Sciences. Microbes On The Tongue Could Be Used To Diagnose Pancreatic Cancer. Researchers at Zhenjiang University School of Medicine, China have found that disruption in the microbial composition of the tongue coating could serve as a biomarker for early-stage pancreatic cancer.

January 2019

01/17/2019 - EurekAlert! New Combination Blood tTest for Pancreatic Cancer May Catch Disease Earlier. A team led by Van Andel Research Institute (VARI) scientists has developed a new, simple blood test that, when combined with an existing test, detects nearly 70 percent of pancreatic cancers with a less than 5 percent false-positive rate. The results of the blinded study were published in Clinical Cancer Research, a journal of the American Association for Cancer Research.

01/09/2019 - Let's Win PC. Pancreatic Cancer: 2018 Highlights And Looking Forward to 2019. In the past decade, remarkable strides have been made in the prevention, early detection, treatment, and research of more than 100 different types of the disease we know as cancer.

01/04/2019 - Forbes. New Clinical Trial Aims To Detect Cancer With A Quick Breathalyzer Test Vaccine, Checkpoint Drugs Combination Shows Promise for Pancreatic Cancers. Nowadays 'liquid biopsies,' the notion of detecting cancer using only a blood test to detect minute amounts of circulating tumor are fairly well-known. But what if not even a blood test was needed to detect cancer, merely a few lungfuls of air? A new clinical trial in the U.K. is aiming to find out whether this might indeed be possible.

01/03/2019 - EurekAlert! Vaccine, Checkpoint Drugs Combination Shows Promise for Pancreatic Cancers. Researchers at the Johns Hopkins Kimmel Cancer Center discovered a combination of a cancer vaccine with two checkpoint drugs reduced pancreatic cancer tumors in mice, demonstrating a possible pathway for treatment of people with pancreatic cancers whose response to standard immunotherapy is poor.

December 2018

12/19/2018 - HealthDay News. Chemo 'Cocktail' Embraced as Pancreatic Cancer Breakthrough. When researchers announced that a four-drug chemotherapy regimen can add years to the lives of some patients with earlier-stage pancreatic cancer, doctors didn't wait.

12/12/2018 - Michigan Health. Why Every Pancreatic Cancer Patient Should Consider Genetic Testing. An expert panel finds an inherited risk in 1 in 10 pancreatic cancer cases, leading to new recommendations advising all patients to consider genetic screening.

October 2018

10/30/2018 - People. 13-Year-Old Creates Tool to Help Pancreatic Cancer Patients During Radiotherapy. A middle school student from Portland, Oregon is helping doctors improve the results of radiotherapy for pancreatic cancer patients. Rishab Jain, 13, was recently awarded the honor of America’s Top Young Scientist by Discovery Education and 3M for an invention that makes radiotherapy more effective.

10/01/2018 - Time. Nobel Prize in Medicine Awarded for Immune System Cancer Research. The Nobel Prize in medicine was awarded Monday to two researchers from the United States and Japan for advances in discovering how the body’s immune system can fight off the scourge of cancer. The 9-million-kronor ($1.01 million) prize will be shared by James Allison of the University of Texas Austin and Tasuku Honjo of Kyoto University.

August 2018 

08/15/2018 - New York Times. Can You Screen for Early Pancreatic Cancer? Pancreatic cancer is the fourth leading cause of cancer death in the United States, claiming some 44,330 lives a year, but there is currently no standard screening test that can detect this cancer early and “has actually been proven to save lives,” said Dr. Otis Brawley, chief medical and scientific officer for the American Cancer Society.

June 2018

06/26/2018 - CNN. Study: 'Artificial Pancreas' Better Controls Blood Sugars in Hospital Patients with Type 2 Diabetes. A device some call an artificial pancreas was shown to better control blood sugar levels in hospitalized patients with Type 2 diabetes compared with those getting insulin manually, according to a study published Monday in the New England Journal of Medicine.

06/19/2018 - Mayo Clinic. Mayo Clinic Discovers Gene Mutations Linked to Pancreatic Cancer, Calls For Expanded Testing. Six genes contain mutations that may be passed down in families, substantially increasing a person’s risk for pancreatic cancer. That's according to Mayo Clinic research published in the June 19 edition of the JAMA. However, because researchers found these genetic mutations in patients with no family history of pancreatic cancer, they are recommending genetic testing for all pancreatic cancer patients as the new standard of care.

06/18/2018 - CNN. Diabetes After 50 Could Be Early Sign of Pancreatic Cancer, Study Says
The study, published Monday in the Journal of the National Cancer Institute, followed nearly 50,000 African-American and Hispanic men and women above the age of 50 for about 20 years. None of the participants had diabetes or pancreatic cancer at the beginning of the study. Of the nearly 50,000 participants, the researchers identified about 16,000 who developed diabetes and about 400 who developed pancreatic cancer during the 20-year study period. Those individuals who developed diabetes were more than twice as likely to develop pancreatic cancer compared with those who did not develop diabetes, according to Wendy Setiawan, associate professor of preventive medicine at the Keck School of Medicine of the University of Southern California and a lead author of the study.

May 2018

05/04/2018 - LA Times. Attention women: Your Choice of Blood Pressure Medicine May Affect Your Risk of Pancreatic Cancer. In a large and intensively-studied group of middle-aged and older women, the risk of developing pancreatic cancer was more than twice as high for those who took a short-acting calcium channel blocker for more than three years.

April 2018

04/16/2018 - AARP. 5 Warning Signs of Pancreatic Cancer. Although pancreatic cancer can be treated if caught early, the signs are often subtle, and the disease is usually missed until it is in later, more serious stages. But there are some warning signs that you can watch out for.

March 2018

03/28/2018 - Becker's Healthcare. 10 Things To Know About Rising Rates Of Pancreatic Cancer. Pancreatic cancer accounts for about 3 percent of all cancers, according to Scientific American, but its incidence continues to grow.

03/14/2018 - Men's Health. 7 Pancreatic Cancer Symptoms Your Doctor Won't Tell You About. While not everyone with pancreatic cancer will exhibit early symptoms, knowing what to look out for can help doctors treat it as soon as possible, which significantly raises your chances of survival.

February 2018

02/28/2018 - Let's Win PC. Precision Medicine From The Get-Go. Rather than wait years for drugs to be developed or new genomic-based treatments to be approved, Dr. Ben George and his colleagues are working with what they already have—but in a smarter way. They are using genomic tools to guide treatment selection and sequencing.

January 2018

01/25/2018 - Medical News Today. Pancreatic Cancer: Modified Flu Virus Destroys Tumors. Researchers from the Queen Mary University of London in the United Kingdom have modified a flu virus and used it to successfully target pancreatic cancer cells.

01/18/2018 - Science. Detection And Localization Of Surgically Resectable Cancers With A Multi-Analyte Blood Test. Since its inception, the Rolfe Foundation has been at the forefront in supporting early detection pancreatic cancer research. We are thrilled to have funded an early detection study at Johns Hopkins that can screen for 8 cancers, through liquid biopsies, including pancreatic cancer. This is a significant step toward saving lives and, ultimately, toward a cure for pancreatic cancer!

01/12/2018 - Times of Israel. Tel Aviv University Study Augurs Hope For Pancreatic Cancer Patients. Researchers find genomic pattern typical of longer-term survivors; develop nanoparticle 'taxi' that delivers tumor suppressors straight to cancer tissue

October 2017

10/04/2017 - Futurity. Test Shows Promise For Detecting Pancreatic Cancer. Researchers have successfully shown that a new genetic test can, with high sensitivity, determine which pancreatic cysts are most likely to be associated with an aggressive form of pancreatic cancer.

September 2017

09/29/2017 - Let's Win. Pancreatic Cancer and Family History. Rolfe Foundation is proud and excited to announce that there is a simple family history tool in the works to help you Know Your Family and Know Your Risk.

09/25/2017 - University of Notre Dame. Notre Dame Research Shows Promising Results For Improving Pancreatic Cancer Treatment. A stress response protein-inhibiting compound may be key to increasing effectiveness of #chemotherapy, according to a study by researchers at the University of Notre Dame.

09/11/2017 - Forbes. A Pill Might Control Pancreatic Cancer, Even If It Doesn't Cure It. So far, these pills are approved only for women with particular genetic findings, and mainly for ovarian cancer and related tumors, such as Fallopian tube cancer.

09/08/2017 - Hopkins Medicine. Rolfe Foundation Helps Fund Hopkins Study. Johns Hopkins scientists say they have developed a blood test that spots tumor-specific DNA and protein biomarkers for early-stage pancreatic cancer.

August 2017

08/25/2017 - MedicalResearch. DNA Analysis Identifies Subtype of Pancreatic Cancer With Good Prognosis. This study was motivated by the emerging promise of precision medicine and the emerging evidence that immunotherapy may have phenomenal efficacy in particular molecular subtypes of cancers.  

08/23/2017 - Let's Win! A Newly Identified Biomarker Panel Shows Promise in Earlier Pancreatic Cancer Detection. While there have been some strides made in the treatment of pancreatic cancer, the majority of patients are diagnosed at later stages of the disease when treatment is less effective.That’s why researchers across the globe have been looking for ways in which pancreatic cancer may be found earlier. It has been a persistent scientific challenge.

July 2017

07/13/2017 - CBS News. Blood Test Holds Promise For Earlier Pancreatic Cancer Detection. Pancreatic cancer is an especially tough cancer to beat because it usually isn't detected until late in the disease. But a new blood test that uses two protein markers is showing promise for picking it up earlier, researchers report.

07/10/2017 - PharamaTimes. Owlstone Medical, CR UK Test Potential Of Breath Test For Cancer. UK diagnostics group Owlstone Medical and Cancer Research UK have kicked off a study aiming to identify breath biomarkers to improve the early detection and diagnosis of multiple cancer types.

07/05/2017 - Shields Gazette. Two Drinks A Day Raises Cancer Risk By 21%. Just two beers or glasses of wine a day raises the risk of bowel and gullet cancer by more than a fifth, according to new research.

June 2017

06/22/2017 - PR Urgent. Rolfe Pancreatic Cancer Foundation Announces Grant To Support Expansion Of Online Early Detection Tools.  The Rolfe Pancreatic Cancer Foundation, a leading Midwest institution with a mission of being a catalyst for the early detection and ultimate cure of pancreatic cancer, today announced a $100,000 grant for Diane Simeone, M.D., Director of the Pancreatic Cancer Center at NYU Langone Medical Center, in partnership with genetic software company Progeny. The grant aims to strengthen a tablet-based pancreatic cancer family history tool to gather complete, detailed familial data and guide clinical care for patients and family members, while improving early detection testing criteria. 

06/22/2017 - Wall Street Pit. Potential Cure For Pancreatic Cancer May Already Be Inside Our Body. All it takes may be a little tweaking and pancreatic cancer patients could have a fighting chance against the disease.

06/22/2017 - CNN. Cancer Research Emerges As Potential Bipartisan Cause Amid Budget Fight. Nadine Takai-Day's brother, Hawaii Democratic Congressman Mark Takai, was the politician in the family. She didn't expect to return to Capitol Hill after her last visit for Takai's memorial service after he succumbed to pancreatic cancer to lobby her brother's former colleagues.

06/06/2017 - Chicago Tribune. 7 Things Doctors Are Buzzing About At The Biggest Cancer Research Meeting. The conference, which opened Friday and wraps up Tuesday, features hundreds of sessions and poster presentations ranging from the highly technical ("Predictive biomarkers of ipilimumab toxicity in metastatic melanoma") to tips for everyday practice ("Patient communication: Balancing hope versus reality"). While most of the topics are as serious as, well, cancer, there are some lighter moments. Here's a look at a few things that have been getting play:

06/01/2017 - Cancer Compass. FDA OKs First Cancer Drug By Genetic Type, Not Organ Of Origin. Many new cancer drugs target genetic "biomarkers" that are specific to tumors -- wherever in the body they may appear. On Tuesday, the U.S. FDA announced that, for the first time, it had approved a cancer drug based on disease genetics rather than the body part where the cancer originated.

May 2017

05/18/2017 - Life Science Daily. Researchers Develop Pancreatic Cancer Early Detection Tool. Harvard University researchers have developed a tool designed to aid in the early detection of pancreatic cancer. The team, which published its findings in Nature Biomedical Engineering 1, revealed insight into light-scattering spectroscopy (LSS), which bounces light off targeted tissue to detect structural changes in the tissue.

05/15/2017 - Richmond Times Dispatch. VCU's New Pancreatic Cancer Treatment Could Improve Outcomes. In March, Fields and a team of Massey providers successfully inserted a CivaSheet into a 70-year-old pancreatic cancer patient from Varina, marking the first time the device has been used to treat pancreatic cancer.

05/05/2017 - News Medical Life Sciences. Can Artificial Sweeteners Reduce Pancreatic Cancer Risk? Due to the fact that late diagnosis often renders surgical and pharmacological treatment ineffective, risk reduction may be a critical method of improving pancreatic cancer survival. Reducing sugar intake could potentially be a way of decreasing the risk of pancreatic cancer.

05/04/2017 - Fortune. This Simple Cancer Test Comes With a Big Caveat. A group of experts at a Wednesday panel during Fortune's second annual Brainstorm Health conference in San Diego focused their session on the hot new technology of "liquid biopsies."

April 2017

04/24/2017 - Click2Houston. New Treatment Option For Patients Diagnosed With Pancreatic Cancer. It's an aggressive form of cancer with few early symptoms, leaving patients limited options once they are diagnosed. But now there's a new treatment for pancreatic cancer that's showing promise and adding years to the lives of patients.

04/21/2017 - Science World Report. New 'Cancer Vaccine' Shows Promising Results. Researchers have developed a new personalized #cancer vaccine that could protect people from tumors or cancerous cells. It has targeted 20 mutated proteins unique to each patient's tumors and has inhibited early relapse in 12 patients with skin cancer.

04/18/2017 - PR Newswire. Newfound Signal Helps Pancreatic Cancer Cells Hide from the Immune System. Researchers have uncovered a critical pathway by which Pancreatic Cancer cells turn off the immune system charged with attacking them.

04/11/2017 - Digital Journal. Pancreatic Cancer Connected To Mouth Bacteria. The oral microbiome (that bacteria found in the mouth) can, if imbalanced, enhance the risk of a person developing Pancreatic Cancer. The finding adds to growing reports about the association between human microbes and disease.

March 2017

03/30/2017 - Medial News Today. Direct Tumor Vaccination Shown To Induce Anti-Tumor Immunity And Increase Survival In A Murine Model Of Pancreatic Cancer. Building on their previous research focusing on vaccination within a tumor (intratumoral) for the most common form of pancreatic cancer, investigators from Rutgers Cancer Institute of New Jersey and Rutgers Robert Wood Johnson Medical School have shown that in a mouse model of early stage resected pancreatic cancer, intratumoral vaccination induces an anti-tumor response that results in a significant improvement in overall survival.

03/27/2017 - The Herald Analyst. Unavoidable DNA Replication Errors Help Fuel Cancer. Heredity and lifestyle get the most blame but new research suggests random chance plays a bigger role than people realize: Healthy cells naturally make errors when they multiply, unavoidable typos in DNA that can leave new cells carrying cancer-prone genetic mutations. Gene mutations cause cancer but what causes the mutations?

03/22/2017 - Mayo Clinic. Slaying the Dragon Of Pancreatic Cancer. “The doctor comes in and gives us the news: ‘You have pancreatic cancer. You’ve got six months to live. Get your stuff together,’” Thomas says. “What do you do?” 

03/14/2017 - Science Daily. Light Scattering Spectroscopy Helps Doctors Identify Early Pancreatic Cancer.  New optical tool predicts malignant potential of cysts with 95 percent accuracy, compared to 58 percent accuracy with current test.

03/06/2017 - MedicalXpress. New Blood Test Could Help Detect And Locate Cancer Early On. Bioengineers at the University of California San Diego have developed a new blood test that could detect cancer—and locate where in the body the tumor is growing.

03/06/2017 - The Conversation. Pancreatic Cancer Wouldn’t Be So Deadly If We Could Just Diagnose It Earlier. Pancreatic cancer is extremely difficult to diagnose. [...] Even with current treatments, only 5% of pancreatic cancer patients survive for five years after diagnosis.

03/01/2017 - Let's Win. An Update on the Whipple Procedure. While inroads have been made in the medical treatment of pancreatic cancer, the best chance for a cure remains surgery. However, most studies show that only about one in five patients are diagnosed with pancreatic cancer that appears to be confined to the pancreas. For some of these patients, potentially curative surgery may be an option. 

February 2017

02/24/2017 - MNT. Role Of Rogue Protein PAK4 Confirmed In Pancreatic Cancer Cells. The work, funded by national charity Pancreatic Cancer Research Fund, uncovers new evidence that PAK4 plays a key role in enabling cancer cells to grow and to spread from the pancreas into other areas of the body, a process called metastasis.

02/23/2017 - EurekAlert! Discovery Of A New Gene Critical In The Development Of Lung And Pancreatic Cancers. Researchers at CIMA of the University of Navarra prove that the inhibition of this gene provokes a drastic reduction in the size of these tumors in different experimental models.

02/22/2017 - MedicalXpress. Researchers Reveal Genetic Links Underlying Neuroendocrine Pancreatic Cancer. An Australian-led international research effort has revealed that genetic changes normally linked to breast, colon and ovarian cancers could also drive a rare form of pancreatic cancer.

02/15/2017 - Let's Win. Developing a Screening Test for Pancreatic Cancer. One of the reasons pancreatic cancer is so difficult to treat is because it does not produce symptoms until after it has spread. There is a great need for a test that can identify this cancer early in the disease process.

02/07/2017 - HiTech Chronical. Cancer Rates In Women 'To Rise Faster Than In Men. According to a recent report by World Health Organization, it is easier and cheaper to cure the disease if diagnosed early. 

02/06/2017 - The Guardian. Trial Finds Combination Of Pancreatic Cancer Drugs Extends Survival. Cancer campaigners are hailing a “monumental leap forward” in pancreatic cancer treatment after a new drug trial significantly extended survival from what is the most lethal form of the disease.

January 2017

01/31/2017 - Business Wire. Tempus and University of Michigan Announce Pancreatic Cancer Collaboration. Tempus, a technology company focused on helping doctors personalize cancer care, and the University of Michigan are partnering to help researchers and physicians to identify customized treatment opportunities for pancreatic cancer patients.

01/26/2017 - Medical News Today. Potentially Reversible Changes In Gene Control 'Prime' Pancreatic Cancer Cells To Spread. A multicenter team of researchers reports that a full genomic analysis of tumor samples from a small number of people who died of pancreatic cancer suggests that chemical changes to DNA that do not affect the DNA sequence itself yet control how it operates confer survival advantages on subsets of pancreatic cancer cells

01/25/2017 - Chicago Sun Times. Cancer Death Rates Declining In Cook County, Study Finds. The likelihood that a cancer diagnosis will lead to death has dropped significantly both in Cook County and across the nation during the past three decades, according to the findings of a new county-by-county study.

01/24/2017 - Eureka Alert. Hearst Foundation Funds TGen Research Into Cancer-Related 'Wasting Syndrome.' Cachexia responsible for more than 30 percent of deaths in cancer patients [...] what can we do to reverse the cachexia we see in patients?

01/23/2017 - Eureka Alert. Pancreatic Tumors Rely On Signals From Surrounding Cells. SALK Scientists find that targeting the interaction between a pancreatic tumor and it's microenvironment could weaken cancer.

01/20/2017 - iTeach Post. New Cancer Treatment For Pancreatic, Stomach And Colon Cancer. "Researchers found a way to develop new cancer treatments. The so called "collateral lethality" might be the answer to several types of cancer such as pancreatic, colon and stomach cancer. Collateral lethality is a therapeutic strategy uses passenger deleted genes as points of selective vulnerability."

01/09/2017 - Perth Now. Researches Test If Medical Cannabis Can Treat Pancreatic Cancer. "PERTH researchers are to test whether medical cannabis can pave a breakthrough in the treatment of pancreatic cancer, one of the most lethal diseases on the planet."

01/03/2017 - CBS Pittsburg. New Treatment Offering Hope To Pancreatic Cancer Patients. "A cancer diagnosis is never a good thing, but pancreatic cancer is especially bad. The chances of surviving it aren’t great, but there’s a new treatment that’s offering hope."

December 2016

12/19/2016 - The Telegraph. Blood Test Which Tells Pancreatic Cancer Patients How Long They Have Left To Live, Developed By Scientists. "Scientists at the Sorbonne University in Paris, discovered that the prognosis for patients is far worse if tumour DNA is found in their blood."

12/15/2016 - Sydney Morning Herald. Australian-First Screening Exposes Pancreatic Cancer In Asymptomatic People. "In the five years, the free screening program has been running, Dr. Stoita and her colleagues have picked up two cases of pancreatic cancer in its early stages, both of which are operable."

12/14/2016 - PharmaBiz. KIMS Doctors Perform Unique Robotic Medical Procedure For Pancreatic Cancer. “Robotic whipples procedure is already being implemented for treating several cancers. However at KIMS we have successfully implemented this unique robotic surgery on three patients suffering from pancreatic cancer in various stages and medical conditions,” informed Dr Madhu.

12/05/2016 - NewsWeek. Tracking Down One Of Cancer's Deadliest Culprits, The RAS Family Of Genes. When it comes to the current state of cancer survival, Susan Bates feels like many of the rest of us. “It’s incredibly frustrating,” she says. For Bates, who treats pancreatic and other cancers at Columbia University Medical Center, the frustration is worsened by virtue of knowing her enemy—an elusive gene that “makes cancer grow very fast.” 

November 2016

11/08/2016 - The Health Site. 6 Common Symptoms Of Pancreatic Cancer. If you suffer from persistent pancreas infection or obesity, the risk of pancreatic cancer is high. Although the exact cause of pancreatic cancer is not known, knowing about its symptoms can help you to diagnose the cancer at an early stage. Dr Deepak Chhabra, Surgical Oncologist, Mumbai sheds light on common symptoms of pancreatic cancer.

October 2016

10/21/2016 - Let's Win. Can A Pancreatic Cancer Screening Test Become A Reality? As the 4th leading cause of cancer death among men and women in the United States, pancreatic cancer often goes unnoticed until it’s incurable.

10/20/2016 - The Sun. GOLD STANDARD. Tiny GOLD particles help fight cancer by carrying drugs to attack tumours. The nanoparticles help stop the spread of ovarian cancer, and now pancreatic cancer - which can be resistant to treatment.

10/11/2016 - Discover. FDA Approves First Artificial Pancreas Faster Than Anyone Expected. Convinced by the study results, the FDA approved Medtronic’s device, called the MiniMed 670G hybrid closed-loop system, for people with type 1 diabetes who are 14 years of age and older. 

10/05/2016 - National Caner Institute. Pancreatic Cancer Cells May Obtain Nutrients From Neighboring Cells. Pancreatic cancer cells grow by instructing neighboring cells to provide them with nutrients, a new study published online August 10 in Naturehas shown.

10/04/2016 - Fred Hutch. A New Model For Pancreatic Cancer Clinical Research. Flexible, precision-medicine trial ‘driven by doing what is best for the individual patient.’

September 2016

09/26/2016 - The Wall Street Journal. Physicians And Physicists Join Forces To Fight Pancreatic Cancer! By bringing together experts from different fields, scientists seek answers to complex medical problems. This is exactly what Rolfe Foundation is talking about when we say that we are Smarter Together.

09/21/2016 - Let's Win. Understanding A Family’s Risk For Pancreatic Cancer. With inherited genetic changes probably playing a role in most pancreatic cancers, researchers are keen to identify people at risk for the disease.

09/19/2016 - The Daily Texan. Cell-Simulating Chip Offers Testing Ground for Cancer Drugs. A gold plated chip that measures the electrical current inside damaged DNA for monitoring the effectiveness of cancer drugs.

09/14/2016 - OncLive. Unfortunately, in Pancreatic Cancer, immune therapy is not making the same strides that we’ve seen with other cancers. And the reason for that is that for immunotherapy to work, it needs a number of things. One of them is that it needs certain immune cells, we call them T cells, to be available around the cancer cell, to be able to destroy the cancer cells when they are stimulated to do so.

09/08/2016 - The Washington Post. Cancer ‘Moonshot’ Panel Names Top 10 Ways To Speed Progress Against The Disease. The Obama administration's "cancer moonshot" took a major step forward Wednesday when a committee of top cancer researchers and patient advocates recommended an ambitious set of scientific goals designed to sharply accelerate progress against the disease.

09/07/2016 - PR Newswire. Immune System Infighting Explains Pancreatic Cancer's Aggression. Internal conflict between cell types explains why the immune system struggles to recognize and attack pancreatic cancer. Curbing this infighting has the potential to make treatment more effective, according to a study led by researchers from NYU Langone Medical Center and its Perlmutter Cancer Center.

09/06/2016 - The Guardian. New Drug 'Wakes Up' Immune System To Fight One Of Deadliest Cancers. This new drug attacks cancer and has extended the lives of people with metastatic pancreatic cancer and has no side-effects, raising hopes for a new and powerful tool against the most intractable form of the disease.

August 2016

08/31/2016 - UofM News. Pancreatic Cancer Uses Alternative Fuel to Grow in a Hostile Environment. Inside a pancreatic tumor is a hostile environment. Cancer cells are choked off from the blood vessels, blocking access to oxygen and nutrients. A metabolic cross-talk pathway between cancer and noncancer cells in pancreatic tumors delivers an alternative nutrient to the cancer cells, facilitating tumor growth.

08/29/2016 - UofG News. Pancreatic Cancer Trial To Make Tumours More Sensitive To Treatment. Cancer Research UK (CRUK) launches a first-of-its-kind pancreatic cancer clinical trial to make cancer cells more responsive to chemotherapy and radiotherapy. The trial, which launches in four hospitals across the UK, will treat pancreatic cancer patients whose cancer has grown too big to be removed by surgery but has not yet spread to other parts of the body.

08/26/2016 - VOX. Cancer Is Now The Leading Cause Of Death in 22 States. Surprisingly, That’s Good News. A 2016 report from the American Cancer Society shows, better cancer detection means more cases are being diagnosed that would have otherwise gone unnoticed.

08/25/2016 - EurekAlert! Johns Hopkins Scientists Track Metabolic Pathways To Find Drug Combination For Pancreatic Cancer. "We have to hit cancer cells from more than one angle, and that's made it important to learn how to combine drugs that hit the right combination of pathways," says Anne Le, M.D., H.D.R..

08/24/2016 - Dana Farber Institute. Can Pancreatic Cancer Be Inherited? Most cases of pancreatic cancer develop for unknown reasons, but about 10 percent occur in families that have a strong history of the disease. That doesn’t mean that if you are a member of such a family you will develop pancreatic cancer, but rather that you are at a higher risk for it.

08/24/2016 - Medical Xpress. Pancreatic Cancer Resists Personalized Medicine - What Researchers Are Doing To Fight Back. A team led by University of Arizona researchers is taking a new, patient-directed approach to treating pancreatic cancer. 

08/23/2016 - DW. Fighting Cancer With Methadone - Making Chemotherapy More Powerful. Certain types of chemotherapy apparently work better, when supplemented with the opioid methadone. 

08/22/2016 - UPI. Compound From Marine Sponge May Reduce Pancreatic Tumor Size. The compound induces programmed cell death of pancreatic tumors, and showed potential efficacy against several other types of cancer in lab tests.

08/18/2016 - Let's Win. The Impact of BRCA is Broader Than Breast and Ovarian Cancer. Research shows that 5% of BRCA2 carriers develop Pancreatic Cancer.

08/16/2016 - Siteman Cancer Center. $10.4 Million Awarded For ‪‎Pancreatic Cancer‬ Research! The award, a prestigious Specialized Program of Research Excellence (SPORE) grant, will help scientists pursue new treatments for the deadliest form of the disease, pancreatic ductal adenocarcinoma, including development of more effective chemotherapies and a vaccine.

08/09/2016 - Medical News Today. Novel drug Therapy Kills Pancreatic Cancer Cells By Reducing Levels of Antioxidants. Reducing levels of antioxidants in pancreatic cancer cells can help kill them, newly published research reveals, suggesting an entirely new treatment strategy for the notoriously lethal illness, in which less than 5 percent of patients survive 5 years.

July 2016

07/28/2016 - Science Daily. Immune-Based Therapy in Mice Shows Promise Against Pancreatic Cancer. A new study in mice has shown that immunotherapy against pancreatic cancer can be effective when given in conjunction with drugs that break up the fibrous tissue in these tumors.

07/13/2016 - Sacramento Bee. Walking, Not Sitting, in Office Meetings Provide Exercise Boost. That may not sound like much, but it ties in with the Centers for Disease Control and Prevention recommendation that Americans get at least 150 minutes of weekly physical activity to stay healthy.

07/12/2016 - EurekaAlert. Study Sheds Light on True Risk for Pancreatic Cancer in Patients with Cysts. A look back at more than half a million patient records has established that patients with pancreatic cysts have a significantly higher overall risk of‪ Pancreatic Cancer‬ compared to those without such cysts.

June 2016

06/10/2016 - NY Times. Microsoft Finds Cancer Clues in Search Queries. Scientists say they may be able to identify internet users who are suffering from pancreatic cancer, even before they have received a diagnosis of the disease.

06/07/2016 - Fox News. New Study Links Pancreatic Cancer to 2 Types of Bacteria Found in Gum Disease. Gum disease may cause more than just bad breath, according to a new study, which points to a connection between periodontal disease as a potential early marker for pancreatic cancer. This could pave the way for early detection!

06/07/2016 - Fortune. The Cancer Biopsy of the Future Could Be a Simple Blood Test. One of the biggest stories so far out of the world’s largest cancer conference doesn’t have to do with a groundbreaking drug, but rather a revolutionary new way of genetically sequencing patients’ cancers that could reduce the need for painful and pricey biopsies.

06/07/2016 - Science Daily. Novel Imaging Model Helps Reveal New Therapeutic Target for Pancreatic Cancer. A new imaging model allowed researchers to track drug resistance, and also revealed a new therapeutic target, which early testing suggests could provide a strategy to arrest Pancreatic Cancer‬ growth.

06/03/2016 - The Telegraph. New Cancer Drug Regime Could Double Survival Rates for Thousands of Patients. "Patients suffering from one of the most deadly types of cancer should be switched to a new drug regime that almost doubles their chance of survival, researchers say.

May 2016

05/25/2016 - Mayo Clinic. Chemo, Radiation, Surgery Combo Boosts Survival for Pancreatic Cancer Patients with Veins Involved. “We’re definitely seeing a revolution,” says Mark Truty, M.D., a gastrointestinal surgical oncologist at Mayo Clinic in Rochester, Minn., “A lot of this has to do with better chemotherapy drugs and use of what we call multimodal therapy: chemotherapy, radiationand then an aggressive operation. Now we can potentially offer these therapies to patients who previously were told they had no options.”

05/25/2016 - Cebu Daily News. High School Research Seeks to Fight Cancer, Reaps Int’l Recognition. Young Scientist Arianwen Rollan, 17, wins global recognition for her research on the anti-tumor properties of malunggay seeds after she lost her grandmother to ‪‎Pancreatic Cancer‬.

05/18/2016 - TED. Good News in the Fight Against Pancreatic Cancer. TED Fellow and biomedical entrepreneur Laura Indolfi is developing a revolutionary way to treat this complex and lethal disease: a drug delivery device that acts as a cage at the site of a tumor, preventing it from spreading and delivering medicine only where it's needed. "We are hoping that one day we can make pancreatic cancer a curable disease," she says.

05/12/2016 - Let's Win. We Are Excited and Proud to Support The Launch of Let's Win! This is an online community for those affected by‪ Pancreatic Cancer‬ to share experiences with innovative science driven treatments and learn about the newest research, breakthroughs and clinical trials. Join us today at and "Let's Win" this battle against pancreatic cancer! 

05/04/2016 - Purdue. Controlling the cholesterol metabolism can reduce ‪Pancreatic Cancer‬ spread to other organs. According to Ji-Xin Cheng, a professor in Purdue University's Weldon School of Biomedical Engineering and Department of Chemistry, they "chose pancreatic cancer to test this approach because it is the most aggressive disease of all the cancers."

April 2016

04/19/2016 - Business-Standard. Indian-American Scientist Engineers T-cells to Treat Pancreatic Cancer. In ground-breaking research, a scientist has engineered T-cells -- a type of immune cells -- to break the pancreatic cancer's physical and immunological walls using immunotherapy.

04/15/2016 - ZeeNews. Implantable Device May Soon Shrink Pancreatic Tumours in Humans. Washington: In pioneering research, researchers from Massachusetts Institute of Technology(MIT) and Massachusetts General Hospital have developed a small, implantable device that delivers chemotherapy drugs directly to pancreatic tumours.

04/13/2016 - Huffington Post. Silicon Valley Billionaire Sean Parker Donates $250 Million To Cancer Immunotherapy Research. Sean Parker’s latest venture, The Parker Institute for Cancer Immunotherapy, will focus on the emerging field of cancer immunotherapy, which harnesses the body’s immune system to fight cancer cells. The Institute aims to ensure members can easily share research discoveries and tools.

March 2016

03/02/2016 - Blasting News. Effective Immunotherapy Treatments for Pancreatic Cancer are on the Horizon. A better understanding of the types and weaknesses of pancreatic cancer has been achieved.

February 2016

02/25/2016 - BBC News.